The Aim is to Estimate the Total Amount of Insulin-producing Cells in the Pancreas by MRI.

Pfizer

Status: Terminated

Conditions: Diabetes Mellitus

Treatments: Procedure: MR imaging; Drug: Arginine; Procedure: Glucose clamp

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00280085

A9001280

Details and patient eligibility

About

Assess pancreatic beta cell function using MR imaging.

Full description

The study was terminated on July 31st, 2007. The study was discontinued, as we have not met the primary end point, differentiation between normal volunteers and subjects with type 1 diabetes mellitus. There were no safety concerns.

Enrollment: 29 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal Volunteers
• T1DM and T2DM subjects

Exclusion criteria

• Concomitant severe conditions

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)