The Analgesic Efficacy of Transversus Abdominis Plane Block After Laparoscopic Cholecystectomy

Glostrup University Hospital, Copenhagen

Status and phase: Completed; Phase 4

Conditions: Laparoscopic Cholecystectomy

Treatments: Procedure: transversus abdominis plane block; Procedure: TAP block placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01046071

2009-017420-75 (EudraCT Number)

SM1-plp-09

Details and patient eligibility

About

The purpose of this study is to determine whether Transversus abdominis plane block as part of a multimodal postoperative regimen is superior to control in analgesic efficacy after laparoscopic cholecystectomy.

Enrollment: 80 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Laparoscopic cholecystectomy
• ASA 1-3
• BMI 18-35
• Written consent

Exclusion criteria

• Do not understand danish
• Drug allergy
• Pregnancy
• Alcohol or drug abuse
• Chronic pain with consumption of opioids
• Consumption of NSAID, COX2inhibitors or paracetamol within 24 hours before the investigation
• Infection at the needle site.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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80 participants in 2 patient groups, including a placebo group

transversus abdominis plane block

Experimental group

Description:

transversus abdominis plane block with ropivacaine

Treatment:

Procedure: transversus abdominis plane block

block with saline

Placebo Comparator group

Description:

20 ml of isotonic saline bilateral

Treatment:

Procedure: TAP block placebo