The Application of a Mask in Patients With Severe Covid-19 Already Treated With High-flow Nasal Cannula.

Region Skane

Status: Completed

Conditions: Covid19

Treatments: Other: oxygen mask

Study type: Interventional

Funder types: Other

Identifiers

NCT04794400

2020-07078

Details and patient eligibility

About

Patients with severe hypoxemic respiratory failure due to Covid-19 are often treated with oxygen delivered through a high-flow nasal cannula (HFNC). This is according to guidelines. We have made the clinical observation that oxygenation sometimes improves when a mask (e.g. oxygen mask or inhalation mask) is applied on top of the HFNC. This has quickly become a clinical routine at intermediary care units at our hospital, where patients with HFNC are offered to test the intervention (mask + HFNC) as part of clinical routine.

This study aims to evaluate this new routine in a standardised way.

Full description

Patients with severe covid-19, treated with HFNC, will be approached for consent. If inclusion critera and no exclusion criteria are fulfilled, baseline measurements will be taken without mask, including arterial blood gas analysis (ABG)

Then a simple oxygen mask will be applied covering nose and mouth, without providing supplemental oxygen. After 30 minutes with mask + HFNC, new measurements will be taken, including ABG.

After 30 minutes, the mask is removed and when steady state occurs, new measurements will be taken, without ABG. Then, the patients could continue using the mask as part of clinical routine

Enrollment: 18 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Verified Covid19 infection
• treatment with HFNC
• Estimated P/F ratio of ≤ 13 KPa

Exclusion criteria

• language barrier
• unable to provide consent
• risk of deterioration due to study

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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18 participants in 1 patient group

Intervention

Experimental group

Description:

An additional oxygen mask was applied for 30 minutes, in patients with ongoing HFNC treatment.

Treatment:

Other: oxygen mask