The Application of Comprehensive Prevention and Treatment Strategy of Placenta Accreta Spectrum Disorders

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Not yet enrolling

Conditions: Placenta Accreta Spectrum

Study type: Observational

Funder types: Other

Identifiers

NCT06477497

2022YFC2704505

Details and patient eligibility

About

Placenta accreta spectrum (PAS) disorders are pathological attachment of the placenta to myometrium, where trophoblastic cells invade the uterine placental interface. PAS can lead to severe postpartum hemorrhage or even maternal death. Prenatal diagnosis of PAS is essential for optimal obstetric management to improve the pregnancy outcomes. However, in some low resource regions in China, less than 20% PAS are detected before delivery.

To explore the feasibility and universality of the bundled prevention and treatment strategy for placenta accreta spectrum disorders in different levels of medical institutions, and to investigate its effectiveness in improving the specialized disease management capabilities of medical institutions at all levels. We will conduct a regional, cluster-randomized trial to assess a multicomponent PAS management strategy to improve the prepartum detection rate of PAS.

Enrollment: 33 estimated patients

Sex: Female

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Pregnant women who have regular prenatal examination at the research hospitals
• Pregnant women diagnosed with PAS before or after delivery

Exclusion criteria

• Pregnant women who have never been diagnosed with placental implantation disease throughout the pregnancy
• Pregnant women who were lost to follow-up during the study period

Trial design

33 participants in 2 patient groups

study group

Description:

Theoretical training, technical supporting and standardized referral process

control group

Description:

usual care