The Application of Indocyanine-Green(ICG) Fluorescence Imaging in Hepatocellular Carcinoma

Zhujiang Hospital

Status and phase: Unknown; Phase 1

Conditions: Hepatocellular Carcinoma

Treatments: Drug: Indocyanine-Green(ICG)

Study type: Interventional

Funder types: Other

Identifiers

NCT03793322

201803

Details and patient eligibility

About

This study aims to evaluate the feasibility of indocyanine green (ICG)-based fluorescence imaging in the detection of liver tumors. By correlating the ICG fluorescence patterns with pathologically confirmed tumors , it would be possible to use fluorescence navigation system in helping promoting oncology treatment.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years≤ Age ≤70 years
• Compling with the diagnosis criteria of hepatic carcinoma.
• Primary hepatic carcinoma without intrahepatic or extrahepatic extensive cancer metastasis, the metastatic hepatic carcinoma whose primary focal has been controlled.
• Preoperative liver function is Child - Pugh grade A or B.
• The patients are volunteered for the study.

Exclusion criteria

• Patients with mental illness.
• Patients can't tolerate the operation owe to a variety of basic diseases (such as severe cardiopulmonary insufficiency, renal insufficiency, cachexia and blood system diseases, etc.
• The patients refused to take part in the study.
• There are other co-existed malignant tumors.
• Benign liver diseases.
• Indocyanine green allergy

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 1 patient group

Indocyanine-Green(ICG) injection group

Experimental group

Treatment:

Drug: Indocyanine-Green(ICG)