The Application of the New Magnetic Resonance UTE Technique in Thoracic Lesions

Fifth Affiliated Hospital, Sun Yat-Sen University

Status: Enrolling

Conditions: Lung Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT05998707

ZDWY.FSK.024

Details and patient eligibility

About

Quantitative characteristic values of lung lesions were obtained by UTE technique, so as to make qualitative diagnosis of benign and malignant lesions. And to explore the clinical feasibility of CT-like technology - high resolution ZTE technology in the diagnosis of pulmonary diseases.

Full description

Ultrashort echo time (UTE) sequence can obtain data from T2* for lung imaging before T2* decays in lung parenchyma with extremely short echo time, which makes up for the defect that conventional MRI cannot clearly display short T2 tissue imaging, and can provide more supplementary information for lung CT scan. There has been a lot of research progress in the evaluation of neonatal lung disease, chronic obstructive airway disease and pneumonia. The 3D UTE sequence developed on this basis has made great progress in improving the resolution, signal-to-noise ratio and shortening the scanning time of lung MR Images, and has successfully obtained submillimeter high-resolution images. The purpose of this study was to explore the value of MRI ultra-short echo technology in the qualitative diagnosis of benign and malignant lung lesions, and to explore the clinical application of CT-like technology - high resolution ZTE technology in the lung.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age ≥18 years old;
2. There are lung lesions, and the solid component is ≥6mm;
3. Chest CT plain scan or /+ enhanced examination within 4 weeks.

Exclusion criteria

1. There are metal implants in the corresponding parts of the chest;
2. MRI contrast agent allergy;
3. Claustrophobia;
4. Pregnant women;
5. High fever;
6. Respiratory failure;
7. Lung lesion biopsy within 4 weeks prior to examination.

Trial design

150 participants in 2 patient groups

benign group

Description:

benign lesions in the lung

malignant group

Description:

malignant tumor in the lung