The Assessment of Talar Cartilage in Patients With Unilateral Traumatic Transtibial Amputation

Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Status: Completed

Conditions: Cartilage Degeneration; Traumatic Amputation of Lower Extremity

Treatments: Other: Musculoskeletal ultrasound

Study type: Observational

Funder types: Other

Identifiers

NCT04486534

4

Details and patient eligibility

About

Increased risk of osteoarthritis (OA) has been previously demonstrated in patients with lower limb amputation. Although there are many studies on knee joint of intact limb of amputees in the literature, the number of studies on intact foot and ankle is extremely limited. The primary aim of the study is to compare the intact talar cartilage, tibialis anterior and gastrocnemius muscle thickness measurements of traumatic unilateral transtibial amputee patients with that of healthy individuals using ultrasound. The secondary aim is to investigate the relationship between cartilage and muscle thickness measurements with clinical parameters.

Full description

Methods: A total of 36 patients with unilateral transtibial amputations and 36 age and body mass index (BMI)-matched male controls will be participated in this cross-sectional study. Functional performance will be assessed by 6-minute walking distance (in meter). The Foot and Ankle Outcome Score (FAOS) will be used for the assessment of the symptoms and the functional limitations of the foot and ankle. The health-related quality of life of the subjects will be evaluated with Short Form-36 (SF-36). Subjects' talar cartilage, tibialis anterior and gastrocnemius muscle thickness measurements will be performed using musculoskeletal ultrasound.

Enrollment: 72 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients between the ages of 18-65
• Patients who have been followed up for at least 3 months with the diagnosis of unilateral transtibial amputation
• Patients who have been using prostheses for at least 3 months

Exclusion criteria

• Bilateral amputation
• Previous history of any trauma/surgical history of the lower extremities (other than amputation)
• Rheumatic diseases
• Contracture of the knee and the ankle of the intact limb

Trial design

72 participants in 2 patient groups

Case group

Description:

36 patients between the ages of 18-65, who have been followed up for at least 3 months with the diagnosis of unilateral transtibial amputation and who have been using prostheses for at least 3 months

Treatment:

Other: Musculoskeletal ultrasound

Control group

Description:

36 age and body mass index (BMI)-matched healthy controls

Treatment:

Other: Musculoskeletal ultrasound