The Association Between Epidural Labor Analgesia and Pregnancy Outcomes

Deng Dongrui

Status: Unknown

Conditions: Labor Pain; Psychological Disorder; Pregnancy Outcomes

Treatments: Drug: Ropivacaine Hydrochloride, Sufentanil

Study type: Interventional

Funder types: Other

Identifiers

NCT03381495

TJ-C20171201

Details and patient eligibility

About

Labor analgesia can alleviate intrapartum pain, in the importance of the delivery is very obvious.But some researches think labor analgesia may affect the progress of labor, increase the cesarean section rate.This research adopts the epidural anesthesia to study labor analgesia effects on delivery outcomes and long-term emotional and psychological effects on the mothers. Besides, we also want to study the effect of exercise during pregnancy on the mode of delivery.

Enrollment: 200 estimated patients

Sex: Female

Ages: 15 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

healthy and full term pregnant women

Exclusion criteria

the pregnant women with complications

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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200 participants in 2 patient groups

Epidural analgesia during labor

Experimental group

Description:

The epidural analgesia technique was used to maintain analgesia for parturients who request labor analgesia.First, we injected a test dose of 5ml 1% lidocaine . If not adverse effects were observed 10 minutes after the test dose, the parturient then received a bolus injection of an initial dose of 8-10 ml mixed liquids of 0.075% ropivacaine and 0.2ug/ml sufentanil citrate. We then connected the epidural catheter with a patient-controlled epidural analgesia (PCA) pump, which provided patients the same mixed solution at 8-10ml/h until the delivery of neonates.

Treatment:

Drug: Ropivacaine Hydrochloride, Sufentanil

Non-epidural analgesia during labor

No Intervention group

Description:

Women who refused epidural labor analgesia were included in the non-epidural analgesia group, and they don't receive epidural analgesia during labor