The Association Between Food Timing and Composition on Gastrointestinal Injury, Stress Hormone and Gastrointestinal Complains.

Poznan University of Physical Education

Status: Completed

Conditions: Endothelial Dysfunction

Treatments: Other: 2000 meter ergometer test

Study type: Observational

Funder types: Other

Identifiers

NCT06403241

Rowerscometetive2023

Details and patient eligibility

About

The study aimed to check the influence of timing and composition of diet on markers of gut injury, endotoxemia and stress.

Full description

The research protocol includes detailed food intake analysis, including timing and composition, markers related to the neuroendocrine pathway cortisol, and observations of individually experienced symptoms. Moreover, the study also explores intestinal injury and endotoxemia parameters, such as I-FABP, CLDN-3, and LBP. As a first goal, this study investigates the timing and composition of food intake concerning changes in gut integrity, cortisol levels, and gastrointestinal symptoms. Investigators explored whether an athlete's nutritional intake influences any GI disturbance induced by high-intensity exercise. As a second goal, Investigators tried to connect symptoms and markers from both pathways with gastrointestinal complaints. Investigators hypothesised that cortisol levels would be more profound than other studied parameters in gastrointestinal symptoms.

Enrollment: 13 patients

Sex: Male

Ages: 18 to 23 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Membership in Polish Rowing Team,
• minimum five years of training,
• total training time minimum of 240 minutes,
• filling out a food diary,
• finishing 2000-meter ergometer test.

Exclusion criteria

• Probiotics within the last three months,
• prebiotics within the last three months
• antibiotic therapy within the last three months,
• dietary regime,
• gastrointestinal diseases,
• lactose intolerance