the Association Between Obesity and Early Puberty

Shenzhen Center for Disease Control and Prevention

Status: Completed

Conditions: Early Puberty

Study type: Observational

Funder types: Other

Identifiers

NCT04317014

szCDC_2

Details and patient eligibility

About

childhood obesity and early puberty are closely related, but existing reports usually focus on their relationship from the perspective of phenotype. This study was designed to investigate the association between obesity-related genic polymorphisms and the risk of early puberty in Chinese Han girls.

Full description

the genotypes of obesity-related SNPs were determined and the unstimulated luteinizing hormone, follicle stimulating hormone and estradiol levels were also detected.

Enrollment: 628 patients

Sex: Female

Ages: 7 to 10 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of central precocious puberty or early and fast puberty.

Exclusion criteria

• The participants who were not the first visit to the hospital and had been treated before.
• The participants who were with endocrine disorders.

Trial design

628 participants in 2 patient groups

cases

Description:

early puberty girls of Han Chinese

controls

Description:

normal development girls of Han Chinese