The Association Between Preoperative CPEX and Postoperative Morbidity Following Oesophagectomy

University of East Anglia

Status: Completed

Conditions: Oesophageal Cancer

Treatments: Diagnostic Test: Cardiopulmonary exercise testing

Study type: Observational

Funder types: Other

Identifiers

NCT03216694

222793

Details and patient eligibility

About

A retrospective hospital-based cohort study of the association between preoperative cardiopulmonary exercise test (CPEX) variables and short-term postoperative morbidity following oesophagectomy.

Full description

The aim of this study is to examine the correlations between preoperative CPEX variables (VO2max and Anaerobic Threshold) and 30 day postoperative all cause morbidity in a sample large enough to allow (should significant associations exist) calculation of a threshold value. Secondary aims are to examine associations between the VO2max, AT and cardiopulmonary, non-cardiopulmonary complications as well as specific complications (atrial fibrillation, pneumonia, and anastomotic leak) as well as 30 and 90 day mortality.

Enrollment: 254 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

i. male and female ii. underwent an oesophagectomy iii. completed a pre-operative CPEX test

Exclusion criteria

i. patients that were unable to complete a full CPEX test ii. emergency or palliative surgery iii. pharyngolaryngo-oesophagectomy iv. oesophagectomy and gastrectomy