The Association of Gut Microbiota With Urinary Tract Infection in Infants

Hallym University Kangnam Sacred Heart Hospital

Status: Withdrawn

Conditions: Urinary Tract Infections

Treatments: Other: The collection of feces

Study type: Observational

Funder types: Other

Identifiers

NCT04615689

Gut microbiota and UTI

Details and patient eligibility

About

This prospective case-control study will compare the gut microbiota between the infants with febrile urinary tract infection and healthy infants.

Full description

The investigators hypothesize that the gut environment reflected by intestinal microbiota influences the risk of urinary tract infection. This prospective case-control study will compare the gut microbiota between the infants with febrile urinary tract infection and healthy infants. The investigators will sequence the V3-V4 of the bacterial 16SrRNA genes from the feces and analyze the sequencing data by QIIME2.

Sex: All

Ages: 6 to 15 months old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of febrile urinary tract infection.
• Infants

Exclusion criteria

• Congenital kidney disease
• Congenital heart disease
• Other metabolic disease

Trial design

0 participants in 2 patient groups

Infants with febrile urinary tract infection

Description:

The investigators will recruit infants hospitalized for acute febrile urinary tract infection. Before starting antibiotics treatment, The investigators will collect feces with the informed consents from infants' parents.

Treatment:

Other: The collection of feces

Healthy infants

Description:

The investigators will recruit healthy controls from the clinics for routine check up with the informed consents from infants' parents.

Treatment:

Other: The collection of feces