The Becoming of Children With Doose Syndrome (DOOSE)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Learning Disabilities; Doose Syndrome; Epileptic Syndromes

Treatments: Other: questionnaire

Study type: Observational

Funder types: Other

Identifiers

NCT04048213

PI2018_843_0058

Details and patient eligibility

About

Doose syndrome is a rare epileptic syndrome that can lead to learning difficulties and a poor quality of life. The goal of this study is to evaluate the evolution of epilepsy and its consequences on cognitive development and learning issues in children with Doose syndrome.

Full description

Doose syndrome is a rare epileptic syndrome beginning between ages two and five, characterized by myoclonic-astatic seizures which can be associated with myoclonic seizures, astatic seizures, absences and generalized tonic-clonic seizures. These seizures can be difficult to treat effectively and may lead to learning difficulties. During this study, parents of children with Doose syndrome will receive a questionnaire regarding learning disabilities, quality of life and epilepsy of their children.

Enrollment: 50 estimated patients

Sex: All

Ages: 1 to 6 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• children with doose syndrome diagnosed between ages 1 and 6
• normal development until onset of seizures

Exclusion criteria

• unconfirmed diagnoses
• abnormal diagnoses
• abnormal psychomotor development before onset of seizures
• cerebral MRI abnormalities
• other child epileptic syndromes