The Biodistribution of 1-L-(2 Deoxy-2,- 18 Fluoroarabinofuranosyl) Cytosine ([18F]L-FAC) in Healthy Subjects and Patients With Cancer, Autoimmune and Inflammatory Diseases

Jonsson Comprehensive Cancer Center

Status: Completed

Conditions: Cancer; Autoimmune Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT01180868

DE-PS02-08ER08-01 (Other Grant/Funding Number)

CIRM No. RT1-01126-1 (Other Grant/Funding Number)

08-02-049

Details and patient eligibility

About

The purpose of this study is to determine the biodistribution of a new agent 1-L-(2 deoxy-2,-18fluoroarabinofuranosyl) cytosine non-invasively in healthy humans and to evaluate whether it can be used to image cancer, autoimmune disease, and inflammation

Enrollment: 1 patient

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• greater than 18 years of age
• women of childbearing potential will undergo a pregnancy test free of charge
• patients with hematological malignancies, solid tumors or autoimmune disorders

Trial design

1 participants in 3 patient groups

patients with cancer

Description:

patients with hematological malignancies and solid tumors

patients with autoimmune dosorders

Description:

patients with Rheumatoid arthritis, Crohns's disease, systemic lupus erythematosus.

healthy subjects