The Biology of Claudin 3 in Primary Human Mammary Epithelial Cell Culture

Hackensack Meridian Health

Status: Terminated

Conditions: Breast Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT00481585

07.01.041

Details and patient eligibility

About

The objective of the present study is to determine whether or not primary human mammary epithelial cells are competent for use in molecular studies of transepithelial electrophysiology focusing on the function of the tight junction protein claudin 3.

Human breast Tissue will be removed from mastectomy specimens and used as a source to generate epithelial cells for study.

Enrollment: 13 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects of this pilot study are limited to those female patients who are undergoing therapeutic or prophylactic mastectomy procedures conducted by the department of Surgery at HUMC.

Exclusion criteria

• From within this population, no exclusion criteria shall be applied based on age, race, ethnicity, gender, HIV status, or menopause.