The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue

University Hospital of Limerick

Status: Enrolling

Conditions: Vascular Diseases

Treatments: Other: No intervention.

Study type: Observational

Funder types: Other

Identifiers

NCT05802706

DVS008

Details and patient eligibility

About

This cross-sectional study aims to ascertain the mechanical properties of human carotid/femoral atherosclerotic plaque and abdominal aortic aneurysm tissue and correlate tissue mechanics with novel blood-based biomarkers of cardiovascular calcification.

Full description

The study is a non-randomised, controlled, cross-sectional study of diseased human carotid, femoral and abdominal aortic tissue.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with arterial plaque undergoing treatment where the plaque tissue will be surgically removed as per the usual peripheral endarterectomy procedure.
• Able to provide informed consent.

Exclusion criteria

• Patients that are unable to give informed consent.
• Seriously ill/unconscious patients.