The Bone Metabolism Characteristics of Premature Ovarian Insufficiency (POI)

Shi Yun

Status: Enrolling

Conditions: Bone Mineral Density; Bone Diseases, Metabolic; Premature Ovarian Insufficiency

Treatments: Diagnostic Test: Testing the serum levels of bone metabolic markers

Study type: Observational

Funder types: Other

Identifiers

NCT06339489

2022DZMEC-PG-34

Details and patient eligibility

About

Explore the bone metabolism characteristics of premature ovarian insufficiency.

Full description

Explore the bone metabolism characteristics of premature ovarian insufficiency, indexes includes serum levels of TRACP-5b and BALP, BMD values of lumbar spine L1-L4, left and right hip, left and right femoral neck et.al.

Enrollment: 60 estimated patients

Sex: Female

Ages: 18 to 39 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients diagnosed by Western medicine with premature ovarian insufficiency. 18 ≤ patients' age ≤ 39 years;. Patients who voluntarily participate in this study, sign an informed consent form.

Exclusion criteria

Patients with congenital gonadal dysplasia or a family history similar to "early menopause".

POI patients with acquired organic lesions or ovarian surgery. Patients who have taken Western or herbal medicine artificial cycle therapy or other endocrine therapy in the past three months.

Patients with serious primary diseases and mental disorders such as cardiovascular and cerebrovascular, liver, kidney and hematopoietic system.

Patients who are breastfeeding or pregnant.

Trial design

60 participants in 1 patient group

POI Group

Description:

The patients with premature ovarian insufficiency

Treatment:

Diagnostic Test: Testing the serum levels of bone metabolic markers