The Burden of COVID-19 Survivorship

Mayo Clinic

Status

Completed

Conditions

Covid19

Treatments

Other: Exercise Training

Study type

Interventional

Funder types

Other

Identifiers

NCT04913129

21-002693

Details and patient eligibility

About

This research study is being done to find out what the longer-term physiological consequences of COVID-19 are, and to determine if exercise therapy can help improve lung function, heart function and overall fitness, and reduce symptoms in people recovering from SARS-CoV-2.

Full description

The purpose of this research is to see if taking part in structured exercise training will improve the ability to exercise, the function of the lungs and the function of the heart, and reduce symptoms of fatigue and breathlessness in people recovering from COVID-19. After enrollment all patients will complete exercise testing, lung function testing, and cardiac imaging. Patients will be randomized to either 8 weeks of exercise training (4-5 times per week) or will continue standard medical care. All patients will undergo detailed exercise testing, lung function testing, and cardiac imaging after the intervention.

Enrollment

27 patients

Sex

All

Ages

21 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Aged 21 to 75 years.
History of RT-PCR proven SARS-CoV-2 infection.
Deemed 'recovered' from SARS-CoV-2 infection.
Not clinically obese (BMI ≥ 36) and/or suffer from musculoskeletal or other conditions that would limit exercise participation.
No evidence of cardiac ischemia at rest or during exertion (via ECG).
Able to provide written informed consent.

Exclusion criteria

Individuals less than 21 or more than 75 years old.
Not able to take part in structured exercise training due to injury or other conditions that would put person at risk during exercise.
Unable to provide written informed consent.