The Burden of (Neuro)Cysticercosis Among People Living With HIV in Rural Tanzania (CYSTINET_Tz)

Technical University of Munich

Status

Completed

Conditions

Neurocysticercosis

HIV/AIDS

Treatments

Diagnostic Test: Diagnosis of (Neuro)cysticercosis

Study type

Observational

Funder types

Other

Identifiers

NCT03851419

CYSTINET-Africa Tz II

Details and patient eligibility

About

This study aims to compare the burden of neurocysticercosis among people living with HIV to people not infected with HIV.

Full description

People living with HIV and matched HIV negative controls will be tested serologically for cysticercosis, examined neurologically and will undergo CT scanning to determine the prevalence and presentation of NCC.

Furthermore, the immune system response in HIV patients with Taenia solium neurocysticercosis will be assessed.

Enrollment

2,584 patients

Sex

All

Ages

14+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patients who consent to participate in the study and testing.
Patients of age 14 years and above
Patient living inside the study catchment area
HIV-positive patients
Patient suspected of taeniasis or cysticercosis/neurocysticercosis

Exclusion criteria

Patients with opportunistic infections.
Study participants taking anthelminthic drugs PZQ and ALB or have received them within the previous 12 months.
Pregnant women
Patients that are seriously ill.
Patients with epilepsy and other mental disorders that impair thoughts and emotions such as psychosis.