The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 1)

Weill Cornell Medicine (WCM)

Status: Completed

Conditions: Chronic Obstructive Pulmonary Disease (COPD)

Treatments: Other: CAPTURE Tool

Study type: Observational

Funder types: Other; NETWORK; NIH

Identifiers

NCT03581227

R01HL136682-01 (U.S. NIH Grant/Contract)

1803019032-1

Details and patient eligibility

About

A prospective multi-center study to define the sensitivity and specificity of CAPTURE for identifying previously undiagnosed patients with clinically significant COPD in a broad range of primary care settings.

Full description

The CAPTURE tool consists of a 5-item self-administered questionnaire and selected use of peak expiratory flow (PEF) measurement, designed to identify clinically significant COPD.

For Aim 1 approximately 5,000 patients will be recruited across 100 participating primary care clinics. Eligible participants will undergo a baseline visit during which the CAPTURE tool and PEF will be obtained, as well as spirometry and other participant characteristics.

Enrollment: 4,679 patients

Sex: All

Ages: 45 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Provision of signed and dated informed consent form
2. Stated willingness to comply with all study procedures and availability for the duration of the study
3. Male or female, aged 45-80 years

Exclusion criteria

1. Previous clinician provided diagnosis of COPD

2. Treated respiratory infection (with antibiotics and/or systemic steroids) in the past 30 days of baseline

3. Participants unable to perform spirometry due to any of the following conditions within the past 30 days of baseline

   1. Chest surgery
   2. Abdominal surgery
   3. Eye surgery
   4. Heart attack
   5. Stroke

Trial design

4,679 participants in 1 patient group

Participants without a diagnosis of COPD

Description:

Men and women aged 45 to 80, who have not been diagnosed with Chronic Obstructive Pulmonary Disease (COPD)

Treatment:

Other: CAPTURE Tool