The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique

University of Genova

Status: Not yet enrolling

Conditions: Postcardiotomy Heart Failure; ARDS (Acute Respiratory Distress Syndrome); Intoxication; Drepanocytosis and Thoracic Syndrome; Cardiac Arrest (CA); Ischemic or Valvular Heart Failure; Acute Respiratory Failure; Pulmonary Thromboembolisms; Cardiogenic Shock; Malignant Arrhythmias; Sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT07351435

18-11-2025 CHUM CVT

Details and patient eligibility

About

The project's main goal is to collect baseline clinical and procedural data as well as to assess clinical outcomes for all patients undergoing VV, VA or VAV ECMO implantation in the French West Indies and Guiana. All patients undergoing ECMO implantation will be prospectively registered.

Full description

In the Caribbean region, access to advanced cardiac interventions faces difficulties owing to unequal distribution of health care resources, medical shortages and distance between health care centers in various islands.

At the University Hospital of Martinique (UHM) in Fort de France, a mobile ECMO team is available 24h a day, 7 days a week, for cardiopulmonary mechanical support in the French Overseas Territories and neighboring islands.

Implantation of veno-venous or veno-arterial (VV or VA) ECMO can be performed at the UHM or at remote hospitals. Some patients on VA-ECMO are transfered by airflight to the UHM and/or to French mainland whenever cardiac transplantation is indicated.

Since 2010, the ECMO-UHM database is a prospective event-driven registry housed and updated by the HeartTeam (perfusionnists, emergency and ICU physicians, cardiac surgeons, cardiothoracic anesthesiologists, cardiologists).

Enrollment: 1,200 estimated patients

Sex: All

Ages: Under 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All consecutive patients implanted with a veno-venous extracorporeal membrane oxygenation device or extracorporeal membrane oxygenation device by the HeartTeam from the University Hospital of Martinique (UHM) from January 2010

Exclusion criteria

• Patients with incomplete data (primary endpoint and less than 80% secondary study outcomes)

Trial design

1,200 participants in 3 patient groups

VV-ECMO

Description:

Patients with respiratory failure

VA-ECMO

Description:

Patients with cardiac failure or combined cardiopulmonary failure

VAV-ECMO

Description:

Patients initially on VV or VA-ECMO who require additional respiratory/circulatory support