The China-Anhui Birth Cohort Study (C-ABCS)

Fangbiao Tao

Status: Completed

Conditions: Children Development; Birth Defects; Other Pregnancy With Abortive Outcome; Environmental Exposures

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT02391610

2008020

Details and patient eligibility

About

The China-Anhui Birth Cohort Study (C-ABCS) was set up to examine the delayed, cumulative and interactive effects of maternal environmental exposures on birth outcomes and children's development. The C-ABCS recruited pregnant women from six major cities of Anhui province, China, between November 2008 and October 2010. A range of data (including demographic, obstetric, occupational, nutritional and psychosocial factors) were collected by both interviews and laboratory tests. In each trimester, women's blood samples were drawn, and pregnancy complications were abstracted from physician's medical records. By the end of 2011, birth outcomes/birth defects were observed/identified by clinicians within 12 months after the delivery of 11 421 singleton live births of six cities and those outcomes among the remaining 2033 live births are still being observed. In addition, 4668 children from Ma'anshan city will be further followed up during the pre-school period till they reach adolescence to obtain the data on familial environmental exposures as well as children's physical, psychological, behavioural and sexual development. The interview data and information on laboratory examinations are available on request from archives in the Anhui Provincial Key Laboratory of Population Health & Aristogenics.

Enrollment: 16,766 patients

Sex: Female

Ages: 17 to 49 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Having been lived in local city at least 6 months;
2. Establishing maternal card in the hospital for the first time;
3. Gestational week ≤ 16 weeks;
4. Willing to have antenatal checkups and childbirth in the hospital where they establish maternal cards.

Exclusion criteria

1. Women who have abnormities in speaking and can not complete the survey by themselves;
2. Women with mental disorders;
3. Women who plan to leave local places.