The Circadian Rhythm of Potassium and Cystatin C

University of Erlangen-Nürnberg Medical School

Status: Completed

Conditions: Sudden Cardiac Death; Cardiac Arrhythmias

Treatments: Procedure: Blood withdrawal

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01318746

4408

Details and patient eligibility

About

The potassium value is important to prevent cardiac arrhythmias and sudden cardiac death. In patients with renal failure, the potassium value is not stable and tends to raise. Until now there are no data available if the potassium value has a circadian rhythm and if there are individual changes from day to day.

Full description

Potassium and cystatin c is measured every 2 hours during 24 hours, twice. There are two groups of patients: Patients with eGFR < 60 ml/min and patients with eGFR > 60 ml/min

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• at least 18 years old
• normal renal function and impaired renal function (GFR < 60 ml/min) respectively

Exclusion criteria

• pregnancy
• anaemia (Hb<10 mg/dl)

Trial design

30 participants in 2 patient groups

Healthy group

Description:

15 persons with normal renal function

Treatment:

Procedure: Blood withdrawal

Renal failure

Description:

15 persons with renal failure (GFR \< 60 ml/min)

Treatment:

Procedure: Blood withdrawal