The Clinical Application of Adipose-Derived Stem Cells on Facial Rejuvenation (ADSCs)

Xuzhou Medical University

Status: Unknown

Conditions: Facies

Treatments: Biological: Adipose-derived stem cells

Study type: Interventional

Funder types: Other

Identifiers

NCT02923219

XYFY2016-KL020-01

Details and patient eligibility

About

The purpose of this study is to determine whether the adipose-derived stem cells therapy is effective in the treatment of facial rejuvenation.

Full description

This study will be a prospective study of patients who undergo adipose-derived stem cells therapy for facial rejuvenation at the hospital of Xuzhou medical university. The therapy involves injection of patient's own adipose-derived stem cells, which are separated from vacuumed fat obtained through liposuction of abdomen, hip, thigh and so on. It was confirmed the adipose-derived stem cells can be induced differentiation into fat cells, osteoblasts, chondrocytes, muscle cells, endothelial cells and so on under the corresponding condition in the current literature. The therapy has evolved as a less invasive technique for facial rejuvenation compared to more traditional techniques，such as fat cells injection, sodium hyaluronate injection. Through the use of pre and post treatment photos, three-dimensional skin CT, in addition to the therapeutic evaluation, patient satisfaction questionnaire and a clinician assessment, it is our hope that the investigators will confirm the rejuvenating capabilities of adipose-derived stem cells therapy.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Males and females
• Ages18-60
• Patients of all racial and ethnic origins
• Patients of all undergoing facial rejuvenation

Exclusion criteria

• Ages under 18, and above 60
• Female patients in pregnancy or menstrual period
• Patients undergoing facial rejuvenation using other methods including botox injections, chemical peels, face lifts and others
• Patients using blood thinners, aspirin and hormone, that cannot be stopped
• Patients suffering with severe organic disease, such as coronary heart disease, hypertension, diabetes, lung dysfunction and so on
• Patients suffering with mental disease, and acute or chronic infectious diseases

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 1 patient group

Stem cells separation

Experimental group

Description:

Stem cells separation: The adipose-derived stem cells are separated from vacuumed fat obtained through liposuction of abdomen, hip, thigh and so on. It was confirmed the adipose-derived stem cells can be induced differentiation into fat cells under the special condition in the current literature.Stem cells are used to treat wrinkles and facial rejuvenation.

Treatment:

Biological: Adipose-derived stem cells