The Cognitive and Cardiovascular Health in the Elderly Study (COACHES)

University of Limoges (UL)

Status: Terminated

Conditions: Cognitive Diseases

Treatments: Other: Cardiovascular evaluation

Study type: Interventional

Funder types: Other

Identifiers

NCT01979432

I11014

Details and patient eligibility

About

The main objective of this study is to look for the interest forecast of the IPS as infra-clinical cardiovascular marker in the prediction of a change of the cognitive functions (MCI) at the elderly of 70 and more years old without clinical cardiovascular pathology.

Enrollment: 17 patients

Sex: All

Ages: 70+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• free-living community-dwelling men and women aged ≥ 70 years,
• subjects free of clinical CVD related to atherosclerosis
• preserved basic activities of daily living (ADL = 6)
• without cognitive impairment (MMSE≥24)

Exclusion criteria

• subjects with clinical history of any of the following CVD diseases : coronary artery disease (angina, myocardial infarction, coronary revascularization), cerebrovascular disease (stroke, TIA, carotid revascularization), clinical peripheral artery disease (claudication, critical limb ischemia)
• subjects with neurodegenerative, locomotor and ophtalmological diseases unable to perform the cognitive tests
• subjects unable to give written informed consent.

Trial design

17 participants in 1 patient group

Cardiovascular evaluation

Other group

Description:

Measure of the index of systolic pressure Echo doppler Echography Measure of the speed of the wave of pulse and the central pressure

Treatment:

Other: Cardiovascular evaluation