The Comparison Between Epidural and Intravenous Patient-controlled Analgesia for Laparoscopic Gastrectomy

Keimyung University

Status and phase: Completed; Phase 3

Conditions: Gastric Cancer

Treatments: Drug: IV PCA Fentanyl+nefopam+Ramosetron; Drug: Epidural PCA Ropivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT02444897

2012-12-514

Details and patient eligibility

About

This study was designed to assess the effectiveness of epidural patient-controlled analgesia compared to intravenous patient-controlled analgesia in patients undergoing laparoscopic gastrectomy. The investigators hypothesized that epidural PCA would be more effective in pain control than IV PCA even for laparoscopic gastrectomy.

Enrollment: 60 patients

Sex: All

Ages: 19 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Histologically confirmed adenocarcinoma in stomach
• Males or Females, aged≥19 years and ≤80 years
• Scheduled as laparoscopic gastrectomy
• Patient has given their written informed consent to participate in the study

Exclusion criteria

• History of hypersensitivity for analgesics
• Recent history of narcotic analgesics
• Disability of central nerve system
• Uncontrolled co-morbidity

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Epidural PCA group

Experimental group

Description:

Epidural patient-controlled analgesia group

Treatment:

Drug: Epidural PCA Ropivacaine

IV PCA group

Active Comparator group

Description:

Intravenous patient-controlled analgesia

Treatment:

Drug: IV PCA Fentanyl+nefopam+Ramosetron