the Comparison Efficacy of Azithromycin With Doxycycline in the Treatment of Acne Vulgaris

Shahid Beheshti University of Medical Sciences

Status and phase: Unknown; Phase 2

Conditions: Acne

Treatments: Drug: Doxycycline; Drug: Azithromycin

Study type: Interventional

Funder types: Other

Identifiers

NCT00419848

src-hmj-1385

Details and patient eligibility

About

a comparison of efficacy and adverse side effects occurrence of Doxycycline and Azithromycin in the management of moderate acne vulgaris

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Between 18 to 30 year old
• Moderate facial Acne(At least 10 inflammatory lesions with maximum 3 nodules and pseudocysts

Exclusion criteria

• Pregnancy
• Breast Feeding
• Acne Fulminant
• Acne conglobate
• Isotretinoin therapy within past 6 months
• topical treatment in last 2 weeks
• use of systemic antibiotic in the last month
• Hyperandrogenism symptoms
• Menstrual irregularity

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

1

Experimental group

Treatment:

Drug: Azithromycin

2

Active Comparator group

Treatment:

Drug: Doxycycline