The Comparison of Cognition, Depression and Anxiety, and Quality of Life After Hip Fracture Surgery Under General or Regional Anesthesia

University of Zagreb

Status: Unknown

Conditions: Hip Fractures; Quality of Life; Depression, Anxiety; Postoperative Cognitive Dysfunction

Study type: Observational

Funder types: Other

Identifiers

NCT04518839

643-03/20-07/33,380-130/134-20

Details and patient eligibility

About

Postoperative cognitive dysfunction is a relatively common in elderly patients after hip surgery, but exact mechanism of its onset is still unclear as well as contributing factors. There is also increased incidence of depression and anxiety. Both affect the recovery after surgery, slow it down and reduce the quality of life. Patients will be divided into two groups, operated under regional anaesthesia and operated under general anaesthesia, and monitored after surgery. Patients will be tested before and after surgery to evaluate postoperative cognitive deficits, depression and anxiety scale and health-related quality of life questionnaire.

Enrollment: 140 estimated patients

Sex: All

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients intended for surgical treatment of hip fractures ≥ 60 years
• Patients who are category ASA I to ASA III will be included in research
• Sufficient cognitive ability
• Only those patients who have agreed to be participants in the research and have signed the consent for participation and informed consent.

Exclusion criteria

• Patients who refused to participate in the survey and who did not sign informed consent
• Patients with ASA IV or more
• Patients under 60 years
• Severe psychiatric disorders involving the use of psychopharmaceuticals back three months
• All patients who have other fractures in addition to hip fractures
• Polytrauma
• All patients scheduled for more than one surgical intervention during the procedure, or within the next 8 weeks
• Patients who have been diagnosed with dementia, and / or are receiving anti-dementia drugs

Trial design

140 participants in 2 patient groups

Group with regional anaesthesia

Group with general anaesthesia