The Comparison Of Nerve Blocks In Cesarean Delivery

Feng Xia

Status: Completed

Conditions: Anesthesia, Obstetrical

Treatments: Procedure: Intravenous patient controlled analgesia (PCA); Procedure: QLB

Study type: Interventional

Funder types: Other

Identifiers

NCT03333902

[2016]123

Details and patient eligibility

About

The purpose of this study is to investigate the effect of different kinds of popular peripheral nerve blocks for postoperative analgesia after cesarean delivery is completed, compared with traditional epidual analgesia.

Full description

Visual Analogue Scale (VAS) and morphine consumption was adopted to evaluate the pain relief.

Enrollment: 102 patients

Sex: Female

Ages: 24 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists (ASA) physical status I or II
• weight from 50 to 70 kilogrammes
• a normal singleton pregnancy
• ≥37 weeks gestation

Exclusion criteria

• congenital coagulopathy
• anatomic abnormalities
• localized skin infection
• allergy to any of the drugs used

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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102 participants in 4 patient groups

QLB type 2

Experimental group

Description:

Ultrasound-guided, Inject at the point posterior to quadratus lumborum muscle, 0.2% ropivacaine 30mL in each side for a total of 60mL. Subjects also receive an intravenous patient controlled analgesia (PCA) pump of 0.5 mg/mL morphine for 48 hours.

Treatment:

Procedure: QLB

Procedure: Intravenous patient controlled analgesia (PCA)

QLB type 3

Experimental group

Description:

Ultrasound-guided, Inject at the point between the quadratus lumborum and the psoas major muscle, 0.2% ropivacaine 30mL in each side for a total of 60mL. Subjects also receive an intravenous patient controlled analgesia (PCA) pump of 0.5 mg/mL morphine for 48 hours.

Treatment:

Procedure: QLB

Procedure: Intravenous patient controlled analgesia (PCA)

QLB type 2+3

Experimental group

Description:

Ultrasound-guided, conduct both QLB type 2 and 3, 0.2% ropivacaine 15mL in each point of injection, for a total of 60mL. Subjects also receive an intravenous patient controlled analgesia (PCA) pump of 0.5 mg/mL morphine for 48 hours.

Treatment:

Procedure: QLB

Procedure: Intravenous patient controlled analgesia (PCA)

epidural anesthesia group (EA)

Active Comparator group

Description:

Epidural catheter placement was conducted when finishing spinal anesthesia. After surgery, 30 mL saline (placebo) was Injected at the point posterior to the quadratus lumborum in each side for a total of 60mL. We used a single bolus of 0.15% ropivacaine + 2 mg morphine (diluted in 6 ml saline) via epidural cathether. Subjects also receive an intravenous patient controlled analgesia (PCA) pump of 0.5 mg/mL morphine for 48 hours.

Treatment:

Procedure: QLB

Procedure: Intravenous patient controlled analgesia (PCA)

Sponsor of this trial

Lead Sponsor

Feng Xia