The Comparison of Supraperiosteal Nerve Block With Opiate Analgesia in Alleviating the Pain of Toothache

Albany Medical College

Status and phase: Completed; Phase 4

Conditions: Toothache

Treatments: Drug: bupivacaine (supraperiosteal nerve block); Drug: hydrocodone/acetaminophen

Study type: Interventional

Funder types: Other

Identifiers

NCT00574015

2200

Details and patient eligibility

About

This study will compare the degree of pain control provided by two techniques for persons with toothache in an emergency department. The two techniques include;

• standard oral narcotic pain medication
• numbing the tooth with local anesthetic by needle injection

Full description

Background: Toothache is a common complaint among patients presenting to the emergency department. There are two commonly employed methods of alleviating this severe form of pain. Oral opioid analgesia is the most commonly utilized strategy for treating this pain. However, many emergency physicians and dentists employ a local anesthetic technique known as supraperiosteal nerve block. This study will compare the relative efficacy of these techniques.

Patients meeting enrollment criteria will be randomized to either receive a supraperiosteal nerve block or oral hydrocodone 10 mg/acetaminophen 650 mg. They will otherwise be managed identically. Reduction of pain scores between entry and 30 minutes post intervention will be compared as well as numeric pain scores obtained by phone contact 24 hours later. Secondary outcomes will include the proportion of individuals from each group filling prescriptions for pain medication and the number of pain pills taken.

Enrollment: 18 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Involvement of a single tooth
• Percussive tenderness of the crown of the suspect tooth

Exclusion criteria

• Age younger than 18 years
• Women who are breast feeding
• Allergy or intolerance to hydrocodone, bupivacaine or acetaminophen
• Pregnancy
• Involvement of multiple teeth
• Pain resulting from pericoronitis.
• Pain resulting from dental trauma occurring less than 90 days prior
• Pain of more than 96 hours duration
• Facial or neck swelling or tenderness
• Alteration in phonation
• Cognitive impairment
• Concurrent use of opiate analgesics
• Impairment of liver function
• Consumption of more than 4 grams of acetaminophen in the past 24 hours.
• Patients who are visually impaired.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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18 participants in 2 patient groups

oral

Active Comparator group

Description:

administration of oral analgesia

Treatment:

Drug: hydrocodone/acetaminophen

Dental Block

Experimental group

Description:

Administration of supraperiosteal nerve block to effected tooth

Treatment:

Drug: bupivacaine (supraperiosteal nerve block)