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The Connection Between Areas in the Brain of Blind Patients

National Institutes of Health (NIH) logo

National Institutes of Health (NIH)

Status

Completed

Conditions

Healthy
Brain Mapping
Blindness

Treatments

Device: Cadwell rTMS
Drug: O15

Study type

Observational

Funder types

NIH

Identifiers

NCT00001926
990031
99-N-0031

Details and patient eligibility

About

The purpose of this study is to test the belief that specific areas of the brain are connected differently in blind patients than patients with sight. In addition, the study will examine the different anatomical connections between brain areas of patients who became blind early in life versus patients who became blind later.

Full description

The purpose of this protocol is to test the hypothesis that the anatomical connectivity of occipital and somatosensory areas in early blind subjects differs from that in subjects who became blind later in life and from that in sighted volunteers.

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Subjects with late blindness.

Subjects with early blindness.

Sighted volunteers.

Age between 18 and 65 years.

Exclusion criteria

Subjects with personal or family history of seizures or other neurological or demyelinating disorders.

Pregnant women tested after urine pregnancy test.

Subjects with metal in the cranium except mouth.

Subjects with intracardiac lines and implanted medication pumps.

Subjects with increased intracranial pressure as evaluated by clinical means.

Subjects with cardiac pacemakers.

Intake or neuroleptics.

Subjects with blindness secondary to degenerative CNS diseases.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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