The COOKER-BLADDER Trial

Roland Seiler-Blarer

Status: Completed

Conditions: Urinary Bladder Diseases; Diet, Healthy; Oncogenesis

Treatments: Other: Dietary regimens

Study type: Interventional

Funder types: Other

Identifiers

NCT05643963

SZB-URO-23-001

Details and patient eligibility

About

The goal of this interventional study is to test the influence of food intake with characteristics of the urinary bladder. The main questions it aims to answer are:

• How does food intake modify the characteristics of urothelial cells?
• Does change of specific diet regimes influence biomarker characteristics in urine? Participants will follow specific diet regime for a given time period. After completion of this period biomarker assessment is performed. Thereafter the participants follow an opposite diet regime for the same time period with identical biomarker assessment at the end.

Biomarkers within the participants and between the diet regimes will be compared to investigate the influence of food intake on the urinary bladder.

Enrollment: 13 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• no daily medication
• no ongoing medical treatment

Exclusion criteria

• Chronic disease
• Regular medication
• Not willing to follow diet instructions

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Sequential Assignment

Masking: Single Blind

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13 participants in 2 patient groups

Focus on bladder protective diet

Experimental group

Description:

For 12 weeks, healthy volunteers will follow a bladder protective diet.

Treatment:

Other: Dietary regimens

No focus on bladder protective diet

Experimental group

Description:

For 12 weeks, healthy volunteers will not follow a specific diet.

Treatment:

Other: Dietary regimens