The Copmparison of Accuracy of PtcCO2 and in PetCO2 in COPD Patients With NIV Treatment

Zhenfeng He

Status: Unknown

Conditions: COPD

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04258982

GIRH-201927

Details and patient eligibility

About

The chronic obstructive pulmonary disease (COPD) patients with type II respiratory failure always needs PaCO2 test to monitor the changes of disease. Method used mostly nowadays to detect PaCO2 is arterial puncture which is accurate but is invasive, painful and non-dynamic. Noninvasive measurement methods includes end-tidal CO2 (PetCO2), transcutaneous CO2 (PtcCO2) which can monitor the PaCO2 dynamically and noninvasively, but their accuracy is in controversy. Common PetCO2 is especially inaccurate in COPD patients while our team find that the accuracy can be improved by prolong expiration method (PetCO2 (P)).So the investigators want to compare the accuracy of PtcCO2 and PetCO2(P) in AECOPD patients during noninvasive ventilation(NIV).

Enrollment: 10 estimated patients

Sex: All

Ages: 20 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• AECOPD patients with type II respiratory failure who need NIV treatment

Exclusion criteria

• hemodynamics is unstable;
• any other lung disease despite COPD;
• other diseases influencing experiments: Cognitive impairment disease mouth and nose trauma.

Trial design

10 participants in 1 patient group

AECOPD group

Description:

The study incruit AECOPD patients with type II respiratory failure who need the NIV treatment.

Treatment:

Other: no intervention