The Correlation Between Degeneration of Paraspinal Muscle and Outcome of Patients With Lumbar Spinal Stenosis

Peking University

Status: Unknown

Conditions: Paraspinal Muscle; Lumbar Spinal Stenosis

Treatments: Other: observation

Study type: Observational

Funder types: Other

Identifiers

NCT04688944

M2019400

Details and patient eligibility

About

The photographical and functional parameters of paravertebral muscle in patients with lumbar spinal stenosis will be measured to investigate the correlation between paravertebral muscle degeneration and symptoms and prognosis of patients.By measuring the parameters of paravertebral muscle with normal people, the differences between the patients and normal people will be compared to establish an appropriate paravertebral muscle evaluation method.

Full description

It is a prospective observational study. This study will recruit 200 patients with lumbar spinal stenosis who will undertake posterior lumbar decompression and fusion surgery in our hospital.They all take preoperative lumbar mri examination and waist and back muscle strength test as well as recording their preoperative visual analogue scale,oswestry disability index, lumbar stiffness disability index score.All patients will receive a follow-up lasting for 1 year,and we will record patients outcomes,such as visual analogue scale,oswestry disability index and lumbar stiffness disability index score at each follow-up time. At the same time,we will recruit 100 healthy subjects without lumbar diseases or chronic lumbar pain. The difference of their age with patients was less than 5 years. Meanwhile, lumbar dorsal muscle strength test and lumbar mri examination were conducted, and visual analogue scale as well as oswestry disability index and lumbar stiffness disability index score was recorded in healthy subjects.

Enrollment: 200 estimated patients

Sex: All

Ages: 45 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients with lumbar spinal stenosis
• age>45 years old
• without other spinal disease
• without history of former spinal surgery

Exclusion criteria

• With neuromuscular diseases
• With hip joint or knee joint disease
• Acute or severe chronic back pain of spinal stenosis that could interfere with the evaluation of endurance
• Other serious diseases impacting the evaluation of endurance

Trial design

200 participants in 2 patient groups

patients

Description:

(1) age ≥ 45 years, (2) diagnosed LSS through a combination of clinical history, physical examination and radiological changes showing spinal canal stenosis on magnetic resonance imaging

Treatment:

Other: observation

healthy people

Description:

(1) age ≥ 45 years; (2) without chronic low back pain (LBP)