The Correlation Between Genetic Polymorphism, Platelet Activity, Clopidogrel Responsiveness, and Serum Adipokine Concentration in Asian Acute Coronary Syndrome Patients

China Medical University

Status: Unknown

Conditions: Chronic Coronary Artery Disease; Acute Coronary Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT01255267

DMR99-IRB-041

Details and patient eligibility

About

In this study, we evaluate the acute coronary syndrome patients to see if there is correlation between platelet activity, genetic polymorphism (CYP2C19 and ABCB1), serum adipokines level, and Clopidogrel responsiveness.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Age > 18 y/o
2. Acute coronary syndrome patients
3. Chronic coronary artery disease patients
4. Healthy volunteers

Exclusion criteria

1. Patient refusal
2. Allergy to Clopidogrel
3. Receive Gp IIb/IIIa inhibitor simultaneously
4. Cancer history
5. Severe renal and liver function impairment
6. Coagulopathy

Trial design

0 participants in 3 patient groups

Acute coronary syndrome patients

Chronic coronary artery disease patients

Healthy control