The Correlation Study of Hypnotic Drugs on the Cognitive Function of Patients With Chronic Insomnia.

Lili Cao

Status: Invitation-only

Conditions: Insomnia Chronic

Study type: Observational

Funder types: Other

Identifiers

NCT04996953

KUN0802

Details and patient eligibility

About

All the subjects were assessed for sleep quality, anxiety and depression, and cognitive function. Based on their previous hypnotic medication history, they were divided into a non-medicine group and a benzodiazepine group，and the group taking non-benzodiazepine drugs.The cognitive effects of different hypnotic drugs on patients were evaluated by comparing sleep related scale and cognitive function scale.

Full description

Insomnia is one of the most common sleep disorders, with 38.2% of Chinese people suffering from sleep disorders. There are many ways to treat insomnia disorders, but drug therapy is the most commonly used method by medical staff. The cognitive effects of sleep drugs vary in numerous studies, depending on the type and dosage of drugs.This study aims to explore the effects of different types of hypnotic drugs on the treatment of insomnia and cognitive function, hoping to improve the sleep quality and living standards of insomnia patients through this study, and also to obtain some cognitive impairment prevention measures related to insomnia, to provide some theoretical basis for clinical treatment.

Enrollment: 165 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Signed informed consent, male or female ≥18 and ≤75 years old;

2. (ICSD-3) proposed the diagnostic criteria for chronic insomnia;

3. Did not take hypnotic drugs before the visit; 3. Those who took hypnotic drugs before the visit; 4. Can understand and comply with the study protocol;

Exclusion criteria

1. Severe organic disease;
2. Any suicidal behavior in the past 10 years;
3. Those who cannot communicate normally cannot cooperate to complete the scale test;
4. Women who are breastfeeding or pregnant;
5. Medical history that the investigator believes could affect the safety of the subject or interfere with the study evaluation;
6. Currently diagnosed with sleep apnea, narcolepsy and other sleep disorders;
7. Sleep disorders caused by central nervous system diseases, or neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, lewy bodies dementia.

Trial design

165 participants in 1 patient group

165 patients with insomnia