The Crnic Institute Human Trisome Project Biobank (HTP)

University of Colorado Denver (CU Denver)

Status: Enrolling

Conditions: Trisomy 21; Down Syndrome

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT02864108

15-2170

UL1TR001082 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The Human Trisome Project will significantly increase the speed of Down syndrome research and the understanding of associated medical conditions. Its biobank will provide de-identified samples to research.

Full description

The purpose of this study is to provide qualified and approved researchers with access to biological samples and health information to answer specific research questions. This project will significantly increase the speed of Down syndrome research and the understanding of associated medical conditions such as Alzheimer's disease, congenital heart defects, autoimmune disorders, autism, and some forms of leukemia.

Participation includes a blood draw, a mouth swab, and allowing researchers to look at your health information yearly for the next 5 years. Optional procedures include providing a urine and/or stool sample and taking part in the study for a longer time frame.

Enrollment: 2,500 estimated patients

Sex: All

Ages: 6 months to 89 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Anyone 6 months to 89 years old who:

1. has Down syndrome (any type)
2. does not have Down syndrome

Exclusion criteria

1. Prisoners
2. Wards of the state

Trial design

2,500 participants in 2 patient groups

Those with trisomy 21

Description:

People aged 6 months to 89 years old who have some form of trisomy 21.

Controls

Description:

People aged 6 months to 89 years old who do not have trisomy 21. These persons can be related to someone with some form of trisomy 21 but do not have to be related.