The Curative Effect of the Length of the Jejunum Exclusion in Grstric Bypass Surgery for Type 2 Diabetes

Weidong Tong

Status

Completed

Conditions

Obesity

Type 2 Diabetes

Treatments

Procedure: long biliarypancreatic limb

Procedure: short biliarypancreatic limb

Study type

Interventional

Funder types

Other

Identifiers

NCT02667652

776117

Details and patient eligibility

About

The purpose of this study is to investigate the curative effect of the length of the jejunum exclusion in gastric surgry for T2DM and metabolic syndrome,and to draft Scientific and reasonable operation parameters.

Full description

Currently, there is a growing evidence supports the efficacy of Roux-en-Y gastric bypass for the treatment of Type 2 diabetes mellitus. However,there still have a great controversy about the operation parameters. With randomized controlled trial, Patients of BMI>21kg/m2 with type 2 diabetes were randomly divided into two groups: short biliarypancreatic limb:50cm;long biliarypancreatic limb :100cm. The investigators followed-up 3,6,12,24 months of the change of BMI,FBG,HbA1c,Blood pressure,Blood fat after surgery.

Enrollment

50 patients

Sex

All

Ages

20 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Aged 20-65 years old
History of diabetes is less than 15 years
Fasting c-peptide≥1.6
BMI≥21kg/m2；
Ability to understand the nature of the procedure and willing to follow postoperative routine lifestyle and checkups

Exclusion criteria

Psychological and mental disorders
Serious important organs such as heart and lung disease cannot be tolerated surgery
Complex history of abdominal surgery in the abdominal cavity adhesion
Pregnancy or lactation