The Dampness Syndrome of Chinese Medicine Cohort Study (DACOS)

Guangzhou University of Traditional Chinese Medicine

Status: Enrolling

Conditions: Aging; Chronic Disease; Metabolic Disease; Dementia Alzheimers; Cancer; Alzheimer Disease, Early Onset

Treatments: Other: natural aging process

Study type: Observational

Funder types: Other

Identifiers

NCT05315895

SZ2021ZZ06

Details and patient eligibility

About

The researchers plain to build a large-scale, longitudinal, prospective cohort characterized by TCM dampness syndrome. With the biobank of this cohort the investigators want to find the causality between TCM dampness syndrome and clinical chronic diseases and a new way to treat clinical disease.

Full description

DACOS is a national large- scale, longitudinal, multi-center, prospective, cohort study of natural person aged 35 to 75. The baseline survey and the follow-up surveys will be conducted in 5 areas covering the eastern, northern, western, southern and middle parts of China. In this study 100,000 natural person will be regularly followed up for 5 years(visited once a year), with the loss rate ≤15%. Three parts will be carried in the form of interview, physical examination and biological sample collection. During the interview, the investigators plan to do some questionnaires to learn participants' demographic characteristics, life style, disease history, healthy condition(EQ-5D-5L, SDS,), cognition state(AD-8, MMSE, MoCA) and the results of TCM syndrome differentiation(Score of Dampness syndrome and TCM constitution scale). All biological specimens (including blood, feces, urine, saliva and tongue coating) will be collected and stored in the biological resource center until researchers request their use. With the building up of this cohort, the researchers will analyze the causality between dampness syndrome and specific chronic diseases such as diabetes, coronary heart disease, cancer, dementia and so on.

Enrollment: 100,000 estimated patients

Sex: All

Ages: 35 to 79 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Residents aged 30 to 79, whose residence is consistent with their registered permanent residence location;
2. Residents who voluntarily participate in the project, agree to the collection of their biological information, and sign the informed consent form;
3. Residents who have no mental illness and other related diseases, and display a normal ability of expression and understanding;

Exclusion criteria

1. Residents who reject collaboration;
2. Residents who allow no follow-up visits.

Trial design

100,000 participants in 1 patient group

general population

Description:

general population in a specific area and specifc time range.

Treatment:

Other: natural aging process