The Danish Childhood Obesity Biobank

Zealand University Hospital

Status: Enrolling

Conditions: NAFLD, Non-alcoholic Fatty Liver Disease; Obesity; Cardiovascular Diseases; Metabolic Disease

Treatments: Behavioral: A family-centered, multidisciplinary obesity treatment program

Study type: Interventional

Funder types: Other

Identifiers

NCT00928473

250609

Details and patient eligibility

About

The Danish Childhood Obesity Biobank aims to produce a scientific platform for research in obesity: Bio-clinical data are collected from two cohorts - an obesity clinic cohort and a population-based cohort. The biobank thus facilitates translation between research and clinical practice of obesity treatment and related complications.

Full description

The Danish Childhood Obesity Biobank collects data from two cohorts - an obesity clinic cohort and a population-based cohort, of which the latter functions as a reference group.

The biobank continuously and longitudinally includes clinical data and biological samples from children and adolescents in obesity treatment. The population-based cohort has been recruited in a cross-sectional manner from Danish schools, high schools, and dentistries.

Data included in the biobank include venous blood samples, stool, urine, saliva, anthropometrics, body composition by dual-energy X-ray absorptiometry, magnetic resonance imaging and spectroscopy, and genetic markers among others. The data are stored in a central secured electronic database and biological materials are stored in -80-degree Celsius freezers until analyses.

To date, the Danish Childhood Obesity Biobank have included data from more than 5250 children, adolescents and adults from the obesity clinic cohort and more than 4200 from the population-based cohort.

Enrollment: 5,000 estimated patients

Sex: All

Ages: 2 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• 2- 100 Years old
• Adipose, BMI > 90 % percentile

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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5,000 participants in 1 patient group

Lifestyle counseling

Experimental group

Description:

The obese children will start a treatment for obesity in the Children's Obesity Clinic. This treatment includes lifestyle counseling, objective examination, weight-controls, visiting a psychologist, visiting a dietician and blood samples, DXA-scan, eventually MRI.

Treatment:

Behavioral: A family-centered, multidisciplinary obesity treatment program