The Desensitizing Treatment Effects of the Laser and Ozone on Dentin Hypersensitivity: In-vivo Comparison

University of L'Aquila

Status and phase: Completed; Phase 2

Conditions: Dentin Sensitivity

Treatments: Combination Product: Diode laser and desensitized gel; Combination Product: Gas ozone

Study type: Interventional

Funder types: Other

Identifiers

NCT05853523

CONS 01_21

Details and patient eligibility

About

The goal of this split mouth clinical trial is to compare clinical efficacy of diode laser and gas ozone in the treatment of dentine hypersensitivity (DHS) of non-carious-cervical lesion. The main questions it aims to answer are:

• gas ozone affects dentine hypersensitivity?
• diode laser affects dentine hypersensitivity? Participants, affected of DHS , were treated with gas ozone and diode laser.The pain severity was quantified according to the Visual Analogue Scale (VAS) before and after the treatmens.

Enrollment: 44 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Stimulated dentine hypersensitivity greater than 6 on visual analogue scale (VAS)
• DHS affected two teeth, not contiguous, of different mouth semiarch.

Exclusion criteria

• Periodontal surgery in the last 3 month
• Use of desensitizing paste in the last 3 month
• Pregnant or breastfeeding state
• Teeth with caries, reconstructions, pulpits congenital anomalies, fracture, and occlusal interferences.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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44 participants in 2 patient groups

Gas ozone group

Experimental group

Description:

Participant received 32 g/m3 of gas ozone for 30 second.

Treatment:

Combination Product: Gas ozone

Diode laser group

Experimental group

Description:

Participant received an application of desensitized gel, fluoride and potassium nitrate gel , and a first step of an irradiation with diode laser for 20 second of interval, 808 wavelength, and power incrementation, from 0,2 till 0,6 W, not in contact. Then the second step of irradiation for 30 second in contact with dentine surface, 808 wavelength, and power incrementation, from 0,2 till 0,6 W. Then the surface was rinsed, and the irradiation applied for a third time again without the gel as the second step.

Treatment:

Combination Product: Diode laser and desensitized gel