The Development of Diagnostic Biomarker Panels for Hepatitis and Liver Cancer

Ministry of Health, Malaysia

Status: Unknown

Conditions: Carcinoma,Hepatocellular; Hepatitis B,Chronic

Study type: Observational

Funder types: Other

Identifiers

NCT01310062

09-317-3991

Details and patient eligibility

About

More recent studies have shown that the HBV-infected population has a greater risk of development of hepatocellular carcinoma. Nevertheless, there are still a significant number of people chronically infected by HBV who do not develop the complication. Hence, there exist biological markers that could be indicator for the disease-inducing and carcinogenic potential of the virus.

Enrollment: 1,600 estimated patients

Sex: All

Ages: 21+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients of at least 21 years old on day of giving consent for study
• Patients must be able and wiling to give an informed consent
• Patient with chronic HBV infection
• Patient with active hepatocellular carcinoma and chronic hepatitis B
• Healthy subjects

Exclusion criteria

• Patients who have co-infection with HIV or chronic hepatitis C
• Subjects with other types of cancer