The Diagnostic Value of Combinatory EUS and ERCP in Unclear Lesions

Sahlgrenska University Hospital

Status: Completed

Conditions: Neoplasms; Biliary Tract Neoplasms; Biliary Stricture; Biliary Tract Diseases

Treatments: Procedure: Combinatory EUS and ERCP

Study type: Observational

Funder types: Other

Identifiers

NCT03504293

EUS-ERCP Study

Details and patient eligibility

About

ERCP with brush cytology has a poor to moderate accuracy in unclear biliary lesions. Endoscopic ultrasound (EUS) with fine needle aspiration (FNA) for cytology may override some of these shortcomings.

The current prospective study, performed in a tertiary University center, aims to study the feasibility, the accuracy and the clinical value of combinatory ERCP and EUS in unclear biliary lesions.

Full description

The eligible study participants with unclear biliary lesions referred for an ERCP to the Sahlgrenska Univeristy Hospital endoscopy unit will be subjected to ERCP with/without brush cytology followed by EUS with/without FNA.

The results of ERCP and EUS will be compared to the pathology report of surgical specimens in resected patients or to clinical follow up at 12 months post-EUS in non-resected patients.

Enrollment: 90 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with unclear lesions or strictures in the biliary tract referred for endoscopy work up

Exclusion criteria

• Patients unwilling to participate
• Patients unfit for EUS and ERCP