The Diastolic Pressure Gradient for Patients With Acute Coronary Syndrome: Evaluation of Non Culprit Lesions (FORECAST)

University Magna Graecia

Status: Unknown

Conditions: Functional Evaluation of Non Culprit Lesions in ACS Patients

Treatments: Other: Measurement of intracoronary pressure

Study type: Observational

Funder types: Other

Identifiers

NCT01671631

FORECAST

Details and patient eligibility

About

The assessment of non-culprit stenoses is an important issue in ACS. Adenosine administration is currently required for functional evaluation of stenosis severity using the fractional flow reserve (FFR). An alternative adenosine-independent index of coronary stenosis, the instantaneous wave-free ratio (iFR), was recently introduced.

Aim of the present study will be to evaluate the trans-stenotic instantaneous wave-free pressure gradient (iFG), the instantaneous wave-free ratio (iFR) and the fractional flow reserve (FFR) in ACS patients.

Sex: All

Ages: 40 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age 40 to 80 years
• recent Acute Coronary Syndrome
• indication for coronary angiography
• presence of at least one non-culprit lesion requiring functional evaluation with fractional flow reserve (FFR):

Exclusion criteria

• Haemodynamically significant valvular disease
• controindication for Adenosin administration
• previous CABG on the index vessel

Trial design

0 participants in 1 patient group

Acute Coronary Syndrome

Description:

Patients with Acute Coronary Syndrome and multivessel coronary artery disease undergoing functional evaluation of non-culprit lesions.

Treatment:

Other: Measurement of intracoronary pressure