The DIEP-Flap as a Model of Ischemia-Reperfusion

Maastricht University Medical Centre (MUMC)

Status: Completed

Conditions: Ischemia-Reperfusion

Study type: Observational

Funder types: Other

Identifiers

NCT00482469

MEC 07-2-004

Details and patient eligibility

About

It is our goal to study the mechanism of ischemia-reperfusion injury. Our DIEP-operation is actually a clinical model of ischemia-reperfusion. Ischemia-reperfusion injury has never been directly studied in a human, clinical model of autologous transplant.

Enrollment: 45 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient is undergoing a DIEP-breast reconstruction, unilateral as well as bilateral
• is aged 18 years or older

Exclusion criteria

• diabetes mellitus
• diseases of the kidneys
• diseases of the liver
• patients who are taking immunosuppressants