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The Differences Between Gonadal and Extra-gonadal Malignant Teratomas

T

Tongji University

Status

Completed

Conditions

SEER Database

Treatments

Other: survival rates

Study type

Observational

Funder types

Other

Identifiers

NCT04555395
malignant teratomas

Details and patient eligibility

About

A tumor comprising of different types of tissues (such as hair, muscle, bone, etc.) is known as a teratoma. It is a type of germ cell (cells that make sperm or eggs) tumor. When these germ cells have rapid cancerous growth, then such a teratoma is called a malignant teratoma. We have studied the differences between gonadal and extra-gonadal malignant teratomas and the effects of chemotherapy in both genders.

Methods: The samples of 3799 male and 1832 female patients with malignant teratoma samples, between the ages of 1 and 85+ years, were selected from the years 1973 to 2014. Trends in incidence, estimated prevalence, incidence rates, and frequency were calculated in gonadal and extra-gonadal tumors with age adjustment. The fiveyear observed, expected, and relative survival rates were analyzed to study the prognosis.

Enrollment

3,799 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

The registry used in our study was the SEER 9 registries Custom Data (with additional treatment fields), Nov 2016 Submission (1973-2014) < Katrina/Rita Population Adjustment> - Linked to County Attributes -Total United States, 1969-2015 Counties, National Cancer Institute, DCCPS (Division of Cancer Control and Population Sciences), Surveillance Research Program, released April 2017, based on the November 2016 submission.

Trial design

3,799 participants in 4 patient groups

gonadal
Treatment:
Other: survival rates
extra-gonadal
Treatment:
Other: survival rates
chemotherapy
Treatment:
Other: survival rates
without chemotherapy
Treatment:
Other: survival rates

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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