The DINE Study-Diet Intervention to Negate Diabetes Study (Improving Weight Loss Outcomes for African Americans)

The University of Alabama at Birmingham

Status and phase: Completed; Phase 4

Conditions: Hypertension; Diabetes; Insulin Resistance

Treatments: Behavioral: The DASH diet with weight loss; Behavioral: Dairy diet; Behavioral: The DASH diet without weight loss

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00599040

1K23DK068223-01 (U.S. NIH Grant/Contract)

F040719005

Details and patient eligibility

About

The purpose of this study is to determine if what you eat affets your insulin sensitivity when you lose a small amount of weight

Enrollment: 113 patients

Sex: All

Ages: 19+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• African American adults (age ≥ 19)
• Obese (BMI > or equal to 30 kg/m2)
• Otherwise generally healthy

Exclusion criteria

• Diagnoses of diabetes
• Malignancy or other states where weight loss is contraindicated (pregnancy
• Individuals with high blood pressure on medications.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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113 participants in 3 patient groups

Weight loss

Active Comparator group

Description:

Weight loss diet focused on the DASH diet

Treatment:

Behavioral: The DASH diet with weight loss

DASH diet

Active Comparator group

Description:

The DASH diet without weight loss

Treatment:

Behavioral: The DASH diet without weight loss

Diary

Active Comparator group

Description:

Dairy Intervention

Treatment:

Behavioral: Dairy diet