The Dissemination of Consensus Recommendations on Upper Gastrointestinal Bleeding (REASON-II)

McGill University

Status and phase

Completed

Phase 4

Conditions

Peptic Ulcer Hemorrhage

Treatments

Other: Educational intervention

Study type

Interventional

Funder types

Other

Identifiers

NCT00840008

MCT-88113

Details and patient eligibility

About

The purpose of this study is to assess whether adherence to NVUGIB guidelines is improved with implementation of a national, tailored multifaceted intervention. Outcomes include adherence rates to two key endoscopic and pharmacological therapy guidelines together (primary), or adherence to these individually as well as to other recommendations (secondary). Patient outcomes and economic data are also assessed (tertiary).

Full description

Clusters are randomized to receive a published algorithm and guidelines (control group), or a multifaceted, tailored educational intervention (see details in protocol - intervention group). The charts of treated patients with non variceal upper GI bleeding are reviewed and adherence to selected guidelines recorded.

Enrollment

3,157 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age 18 or over.
Treated during the study duration
Primary or secondary discharge diagnoses of NVUGIB (per charted ICD-10 code). Additional confirmation of NVUGIB using endoscopic findings or patient symptoms done as previous.

Exclusion criteria

Patients initially assessed at another institution for the present episode of NVUGIB and subsequently transferred to the participating site with unavailable initial data.
Endoscopy noted no gastro-duodenal ulcer bleeding, to ensure patient homogeneity.