The Distribution of Plasma Drug Concentrations of Beta-lactam Antibiotics in Intensive Care Unit Patients (TDM-ICU)

Linköping University (LiU)

Status: Completed

Conditions: Sepsis

Treatments: Other: No intervention.

Study type: Observational

Funder types: Other

Identifiers

NCT02446392

TDM-ICU

Details and patient eligibility

About

In this project, intensive care unit (ICU) patients treated with beta-lactam antibiotics are included with the aim to investigate the potential underdosing in this patient group. Four regional ICU-clinics are recruiting consecutive patients (n=120) and samples are taken before the next dose is administered for three consecutive days.

Enrollment: 120 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Current treatment with beta-lactam antibiotics and admission to the ICU

Exclusion criteria

• Pregnancy, age below 18 years