The Early Administration of Sodium Thiosulfate Should Help to Reduce the Mortality of Dialysis Patients With Calciphylaxis, From a National Cohort

Centre Hospitalier St Esprit

Status: Unknown

Conditions: Calciphylaxis; Renal Insufficiency, Chronic

Treatments: Drug: Sodium Thiosulfate

Study type: Observational

Funder types: Other

Identifiers

NCT03146793

Centre Hospitalier St Esprit

Details and patient eligibility

About

The national drug safety agency authorizes nominatively the use of sodium thiosulfate in dialysis patients with calciphylaxis. To date, it is the largest global cohort (more 600 patients from 2012 to 2016). We wanted to study retrospectively the fate of these patients at 6 months including mortality. Early use improves effectiveness.

Enrollment: 600 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All dialysis patients with calciphylaxis in France who have obtained a temporary use authorization for sodium thiosulfate by National Agency for the Safety of Medicines

Exclusion criteria

• N/A